The paradoxical relationship between ligamentum flavum hypertrophy and developmental lumbar spinal stenosis
نویسندگان
چکیده
منابع مشابه
The paradoxical relationship between ligamentum flavum hypertrophy and developmental lumbar spinal stenosis
BACKGROUND Ligamentum flavum (LF) hypertrophy is a common cause of lumbar spinal stenosis and is thought to be degeneration-driven. Developmental spinal stenosis (DSS) is characterized by pre-existing narrowed spinal canals and is likely a developmental problem that occurs in childhood. In these cases, the LF may demonstrate different characteristics as compared to degeneration-driven stenosis....
متن کاملHypertrophy of ligamentum flavum in lumbar spinal stenosis associated with increased proteinase inhibitor concentration.
BACKGROUND It is well known that age-related fibrosis, or decreases in the elastin-to-collagen ratio of the ligamentum flavum, along with hypertrophy of the ligamentum flavum, are associated with lumbar spinal stenosis. However, the molecular mechanism by which this fibrosis and hypertrophy develop is unknown. Tissue inhibitors of matrix metalloproteinase (TIMPs) are proteinase inhibitors that ...
متن کاملMicroRNA-221 Regulates Hypertrophy of Ligamentum Flavum in Lumbar Spinal Stenosis by Targeting TIMP-2.
STUDY DESIGN A study of lumbar ligamentum flavum (LF). OBJECTIVE The aim of this study was to identify LF hypertrophy related microRNAs (miRNAs) expression profile and to investigate the role of miRNAs in the development of LF hypertrophy in lumbar spinal stenosis (LSS). SUMMARY OF BACKGROUND DATA Although histologic and biologic literature on LF hypertrophy is available, the pathomechanism...
متن کاملpercutaneous lumbar decompression with spinejet hydrosurgery in the treatment of lumbar spinal stenosis secondary to ligamentum flavum hypertrophy
case presentation an 85 years old patient presented because of intractable right leg pain with minimal activities. she was diagnosed with significant right foraminal stenosis and she failed conservative non-invasive therapies. conclusions percutaneous lumbar hydro decompression can be a promising method for the treatment of the patients with lumbar spinal stenosis and neurogenic claudication se...
متن کاملPercutaneous Lumbar Decompression With SpineJet Hydrosurgery in the Treatment of Lumbar Spinal Stenosis Secondary to Ligamentum Flavum Hypertrophy
INTRODUCTION Lumbar spinal stenosis with symptomatic neurogenic claudication is a frequently encountered clinical entity which requires endoscopic or open spine surgery once the patients fail to respond to conservative therapies. In this case report we present a novel minimally invasive decompression technique using a fluid jet device (HydroCision Inc, Billerica, MA, USA) for a patient with sym...
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ژورنال
عنوان ژورنال: Scoliosis and Spinal Disorders
سال: 2016
ISSN: 2397-1789
DOI: 10.1186/s13013-016-0088-5